Author

Alessandra Tammaro

Amsterdam University Medical CentersORCID 0000-0003-3128-5259Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Jesper KersiD· 2 shared Joris J. T. H. RoelofsiD· 2 shared Loes M. ButteriD· 2 shared Nike Claessen· 2 shared Alessia RomagnoloiD· 1 shared Alexis VariniD· 1 shared Anne C. HespiD· 1 shared Antonio Astorga-Gamaza· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Jesper KersORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chronic exposure to low-concentration urban PM2.5 accelerates maladaptive repair after ischemic injury via mitochondrial dysfunction and lysosomal stress.

Peiqi Sun, Antônio Carlos Parra, Talita Rojas Sanches, Caroline Fernanda Hei Wikuats, Loes M. Butter, Nike Claessen, Hans J. Baelde, Ireen Schimmel, Nicole N. van der Wel, Georges E. Janssens, Riekelt H. Houtkooper, Frédéric Maxime Vaz, Joris J. T. H. Roelofs, Peter Boor, Martin Strauch, , Alessandra Tammaro

This study shows that chronic low-concentration PM2.5 exposure after ischemic injury accelerates CKD through mitochondrial dysfunction and lysosomal stress, with nicotinamide reversing some effects.

bioRxiv · Mar 14, 2026 · PreprintMolecular Biology

NNMT promotes tubular senescence and fibrosis in chronic kidney disease

Lucie Chanvillard, Hildo C. Lantermans, Christopher Wall, Jonathan Thévenet, Loes M. Butter, Loic Tauzin, Nike Claessen, Stefan Christen, Sonia Karaz, Steve Lassueur, Giulia Lizzo, José Luis Sanchez-Garcia, Sylviane Métairon, James A. Holzwarth, Valentina Ferro, , Alessandra Tammaro

This study identifies NNMT as a driver of tubular senescence and fibrosis in CKD, showing its association with senescence markers and protective effects when inhibited.

bioRxiv · Jan 6, 2025 · PreprintCell Biology

Inflammasome Profiling in Human Natural Killer Cells under Pro-inflammatory Stimuli and Solid Organ Transplantation

Antonio Astorga-Gamaza, Inés Muela-Zarzuela, Juan Miguel Suárez-Rivero, Alexis Varin, Maarten Naesens, Alessandra Tammaro, Jesper Kers, Juan López-Pérez, Raquel de la Varga-Martínez, Auxiliadora Mazuecos, Baptiste Lamarthée, Mario D. Cordero

This study shows human NK cells can activate inflammasomes in vitro and in transplant patients, with distinct responses in CD56 subsets and sustained activation in renal dysfunction and transplant rejection.

bioRxiv · Apr 17, 2024 · PreprintImmunology