James V. DeGregori

This study shows that CPR-4, a homologue of human cathepsin B, induces DNA damage and mutagenesis in C. elegans under crowding stress, leading to increased mutation rates and competitive growth advantages.

This study investigates how aging-related inflammation contributes to lung cancer development by analyzing gene expression data and using mouse models to assess the role of inflammation in oncogenesis.

FERMI improves detection of rare somatic mutations by reducing sequencing and library preparation errors, enabling tracking of clonal evolution in leukemia.