Author

Carlo Marchetti

University of Colorado AnschutzORCID 0000-0002-0203-316XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Charles Anthony DinarelloiD· 2 shared Adolfo Gabriele MauroiD· 1 shared Alessandra GhigoiD· 1 shared Andre NavarroiD· 1 shared Andrew E. GoodspeediD· 1 shared Antonio AbbateiD· 1 shared Benjamin W. Van TasselliD· 1 shared Catherine Pham‐DanisiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

Charles Anthony DinarelloORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 3, 2026

OLT1177 (Dapansutrile) inhibits Gasdermin D-dependent IL-1β Release and Pyroptotic Cell Death in Bone Marrow-derived Macrophages

Karl A. Pankratz, Masoom Raza, Jarren Ypil…·Shaikh Muhammad Atif

OLT1177 inhibits IL-1β release and pyroptotic cell death in LPS-treated BMDMs by blocking caspase-1 and GSDMD activation.

DOI 10.64898/2026.05.31.729061

mousebulk RNA-seq

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ImmunologybioRxivPreprintMar 9, 2025

UNCONVENTIONAL INTERLEUKIN-1 SIGNALING IN CARDIAC DYSFUNCTION

Stefano A Toldo, Pratyush Narayan, Eleonora Mezzaroma…·Antonio Abbate

This study investigates unconventional IL-1β signaling via PI3Kγ in cardiomyocytes, showing kinase-independent mechanisms link IL-1β to cardiac dysfunction and potential heart failure treatment insights.

1 citation

mouseexperimental assay

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Cancer BiologyAging and CancerPeer-reviewedOct 30, 2024

Inflammation promotes aging-associated oncogenesis in the lung.

Catherine Pham‐Danis, Shi B. Chia, Hannah A. Scarborough…·James V. DeGregori

This study investigates how aging-related inflammation contributes to lung cancer development by analyzing gene expression data and using mouse models to assess the role of inflammation in oncogenesis.

10 citations

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