Cell BiologybioRxivPreprint
Fundamental transport mechanism of mucin-2 ER-to-Golgi trafficking identifies source of ER stress in inflammatory bowel disease
Margaretha A. J. Morsink, Lena Sophie Koch, Shixian Hu…·Kerensa Broersen
The paper identifies that impaired COPII vesicle enlargement due to reduced TANGO1 expression contributes to ER stress in IBD by affecting mucin-2 secretion.
DOI 10.1101/2024.05.13.593851