The paper investigates how the 2A protein interacts with the RNA genome of cardioviruses to activate ribosomal frameshifting through structural changes in the RNA.

2 citations

experimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 26, 2026

Correlating Structure and Rheology in Ionically Crosslinked Alginate Biopolymer Hydrogels - A Case for Why "Less" can be "More"

Vinay Kopnar, Peter S. Sherin, Sarah P. Graham…·Anders Aufderhorst-Roberts

This study investigates how structural changes in ionically crosslinked alginate hydrogels affect their rheological properties, finding that higher crosslinking can reduce mechanical performance.

DOI 10.64898/2026.07.23.740415

imagingexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 29, 2025

A DNA scaffold approach facilitates 5' labelling of the SARS-CoV-2 RNA pseudoknot for smFRET investigation

Sarah P. Graham, Jemma K. Betts, Timothy D. Craggs…·Steven D. Quinn

This paper develops a DNA scaffold method for 5' labeling of SARS-CoV-2 RNA pseudoknots to study their conformational dynamics using smFRET.

DOI 10.1101/2025.07.29.667457

proteomicsexperimental assay

𝕏 PostBluesky