A protein-dependent riboswitch activates ribosomal frameshifting in cardioviruses
Jemma K. Betts, Cy Michael Jeffries, Tim Casper Passchier, H Kung, Sarah P. Graham, Mahmoud A. S. Abdelhamid, Jamieson A. L. Howard, Timothy D. Craggs, Stephen C. Graham, Ian Brierley, Mark C. Leake, Steven D. Quinn, Chris H. Hill
The paper investigates how the 2A protein interacts with the RNA genome of cardioviruses to activate ribosomal frameshifting through structural changes in the RNA.
Molecular Cell · Aug 21, 2026Peer-reviewedMolecular Biology