Daniel M. Weinberger

This study examines capsule switching in Streptococcus pneumoniae using whole-genome sequences, finding that switching is limited to specific capsule-type pairs and influenced by genetic and ecological factors.

This study shows that pneumococcal growth kinetics are influenced by capsular serotype, lineage, and genetic background rather than specific loci.

This paper develops tiled amplicon sequencing panels for whole-genome sequencing of pathogenic bacteria without culturing, enabling drug resistance classification from clinical samples.

This paper introduces SeroCall, a software tool for accurately quantifying pneumococcal serotypes in mixed samples using whole-genome sequencing.

The paper examines how pneumococcus growth varies with environmental conditions and capsule composition, finding associations between growth characteristics and serotype prevalence.