Xianxiao Zhou

This study identifies ZNF180 as a driver of immunotherapy resistance in melanoma by promoting tumor plasticity and immune suppression through mechanisms involving MHC-I loss, CD155 expression, and CD4 T-cell exclusion.

The paper identifies KLF16 as an inhibitory regulator of osteogenic differentiation through transcriptomic analysis of human iPSC-derived cells and in vivo validation.

The paper examines transcriptomic changes in D1 and D2 medium spiny neurons of the nucleus accumbens after cocaine and morphine exposure, revealing shared and divergent regulatory patterns.

This study analyzes the tissue-specific age dependence of cell receptors involved in SARS-CoV-2 infection and identifies key regulators and host processes hijacked by the virus.

The paper uses single-cell RNA-seq to identify Hhip's role in murine coronal suture development, showing its necessity for maintaining suture mesenchyme and osteogenic fronts.

The paper shows that adolescent social isolation causes sex-specific changes in the medial amygdala's transcriptome and behavior, with Crym playing a key role in these effects.

This study identifies molecular networks and key regulators in Alzheimer’s Disease using integrative genomics and experimental validation.

The paper identifies Zfp189 as a key driver of a transcriptional network promoting stress resilience in prefrontal cortex neurons through CREB regulation.