Author

Rubem F. S. Menna‐Barreto

Instituto Oswaldo CruzORCID 0000-0002-1352-0641Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

Adriano C. CoelhoiD· 2 shared Beatriz C. D. de OliveiraiD· 2 shared Juliana Ide AokiiD· 2 shared Luiz H. C. AssisiD· 2 shared Maria Isabel Nogueira CanoiD· 2 shared Mark Ewusi ShiburahiD· 2 shared Benedito Donizete MenozziiD· 1 shared Débora Andrade-SilvaiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Adriano C. CoelhoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The impact of knocking out the Leishmania major telomerase RNA (LeishTER): from altered cell proliferation to decreased parasite infectivity

Beatriz C. D. de Oliveira, Mark Ewusi Shiburah, Luiz H. C. Assis, Veronica Silva Fontes, Pedro Henrique Gallo-Francisco, Selma Giorgio, Marcelo Meuser-Batista, M. N. C. Soeiro, Rubem F. S. Menna‐Barreto, Juliana Ide Aoki, Adriano C. Coelho, Maria Isabel Nogueira Cano

This study investigates the role of Leishmania major telomerase RNA (LeishTER) by generating knockout parasites, showing reduced proliferation, telomere shortening, and decreased infectivity.

bioRxiv · Nov 10, 2023 · PreprintMolecular Biology

Ablation of telomerase reverse transcriptase in Leishmania major results in a senescent-like phenotype and loss of infectivity

Mark Ewusi Shiburah, Beatriz C. D. de Oliveira, Habtye Bisetegn, Débora Andrade-Silva, Luiz H. C. Assis, Rubem F. S. Menna‐Barreto, Marcos Meuser Batista, Maria de Nazaré Correia Soeiro, Benedito Donizete Menozzi, Hélio Langoni, Juliana Ide Aoki, Adriano Coelho, Maria Isabel Nogueira Cano

This study shows that deleting TERT in Leishmania major causes senescent-like traits and reduced infectivity, suggesting it as a potential drug target.

bioRxiv · Nov 10, 2023 · PreprintMolecular Biology