Author

Anne R. Shim

Northwestern UniversityORCID 0000-0002-1354-2111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:electronic health records· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Luay Matthew AlmassalhaiD· 2 shared Vadim BackmaniD· 2 shared Adam EsheiniD· 1 shared Cody L. DuntoniD· 1 shared Emily M. Pujadas-LiwagiD· 1 shared Eric W. RothiD· 1 shared I Chae YeiD· 1 shared Igal G. SzleiferiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

Luay Matthew AlmassalhaORCID

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2 papers

Recent·Most cited

BiophysicsPLoS ONEPeer-reviewedMay 28, 2024

Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure

Anne R. Shim, Jane Frederick, Emily M. Pujadas-Liwag…·Vadim Backman

This study shows that formamide in 3D FISH distorts nanoscale chromatin structure, while alternative methods like RASER-FISH and CRISPR-Sirius have minimal impact.

14 citations

imagingexperimental assay

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GenomicsbioRxivPreprintMay 14, 2019

Quantifying Three-dimensional Chromatin Organization Utilizing Scanning Transmission Electron Microscopy: ChromSTEM

Yue Li, Eric W. Roth, Vasundhara Agrawal…·Vadim Backman

The paper introduces ChromSTEM, a method to quantify 3D chromatin organization using electron microscopy, and finds chromatin is densely packed with heterochromatin having higher density than euchromatin.

6 citations

humanelectronic health records

𝕏 PostBluesky