Kea Joo Lee

This study shows that adolescent NMDAR hypofunction impairs short-term memory by weakening thalamofrontal synapses, not through interneuron dysfunction.

This study shows that reduced spine density and weakened neck compartmentalization in FCD increase neuronal excitability, contributing to epileptogenesis beyond inhibitory deficits.

Volume EM of one focal cortical dysplasia type I patient shows fewer somatic inhibitory and dendritic excitatory synapses, oversized vesicle-rich excitatory synapses, and thicker myelin.

This paper demonstrates that AUTOTAC, a targeted degradation approach, reduces tau aggregates and improves symptoms in tauopathy models and companion dogs.

This study uses longitudinal multi-omic analyses of a mouse model to show seizure evolution in West syndrome involves synaptic remodeling, gliosis, and proteomic/lipidomic changes over time.

This study investigates how GluN2B regulates silent synapses in addiction memory by affecting AMPAR subunit composition and synaptic maturation after cocaine exposure.

The paper identifies a disinhibitory circuit in the cerebellum that supports synaptic plasticity by suppressing inhibition during climbing fibre input.

This study identifies PTK2 as a suppressor of TDP-43-induced neurotoxicity by regulating p62 phosphorylation and UPS impairment in neuronal cells.