Author

Hyung‐Jun Kim

Korea Brain Research InstituteORCID 0000-0002-3385-5510Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Jaekwang KimiD· 2 shared Sung Bae LeeiD· 2 shared Byung Su KoiD· 1 shared Chang Geon ChungiD· 1 shared Chang Man HaiD· 1 shared Eun Seon Kim· 1 shared In Jun ChaiD· 1 shared Jeong Hyang ParkiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Jaekwang KimORCID

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2 papers

Recent·Most cited

C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent accumulation of Staufen in nucleus

Eun Seon Kim, Chang Geon Chung, Jeong Hyang Park, Byung Su Ko, Sung Soon Park, Yoon Ha Kim, In Jun Cha, Jaekwang Kim, Chang Man Ha, Hyung‐Jun Kim, Sung Bae Lee

The paper shows that Staufen accumulates in the nucleus in a C9orf72-associated Drosophila model and that reducing Staufen dosage mitigates PR toxicity.

Human Molecular Genetics · Mar 25, 2021Peer-reviewedGenetics

PTK2 regulates the UPS impairment via p62 phosphorylation in TDP-43 proteinopathy

Shinrye Lee, Yu‐Mi Jeon, Seyeon Kim, Younghwi Kwon, Myungjin Jo, You-Na Jang, Seongsoo Lee, Jaekwang Kim, Sang Ryong Kim, Kea Joo Lee, Sung Bae Lee, Kiyoung Kim, Hyung‐Jun Kim

This study identifies PTK2 as a suppressor of TDP-43-induced neurotoxicity by regulating p62 phosphorylation and UPS impairment in neuronal cells.

bioRxiv · Jun 25, 2018 · PreprintNeuroscience