Patrick Orson Humbert

This study identifies a new apoptotic morphology, AsyCDM, where apoptotic cells asymmetrically partition nuclear material into apoptotic bodies via ROCK1-dependent actomyosin contraction.

This study identifies CDK9's interaction with a RanGTP-NEMP1-Importin-β complex in erythroid enucleation and shows that importin-β inhibition blocks enucleation.

This study uses histone deacetylase inhibition to reveal a new stage in T cell β-selection, showing how CD28, CD5, Lef1, and CD2 coordinate to regulate the checkpoint.