Whitney C. McFadden

Integrative analysis of rare variants and pathway information shows convergent results between immune pathways, drug targets and epilepsy genes

The paper introduces a Bayesian framework to prioritize risk genes for complex diseases by integrating gene-set information with variant counts, identifying novel epilepsy risk genes and linking them to immune pathways and drug targets.

Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation

This paper uses transcriptomic imputation to identify gene-tissue associations linked to Anorexia Nervosa risk, finding significant links in both brain and metabolic tissues.

Transcriptomic Imputation of Bipolar Disorder and Bipolar subtypes reveals 29 novel associated genes

This study uses transcriptomic imputation to identify 29 novel genes associated with bipolar disorder and its subtypes, revealing biological pathways related to oxidative stress and circadian rhythms.