Päivi Saavalainen

Celiac disease patient derived iPSC small intestinal epithelial cells are more persistent under cytokine stimuli than healthy control cells

The paper compares the response of celiac disease and healthy control iPSC-derived small intestinal epithelial cells to cytokine stimuli, finding attenuated responses in celiac disease cells.

Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility

The paper identifies ten new genes with coding variants linked to Crohn's disease risk using sequencing data from over 30,000 patients and 80,000 controls.

Clustering based approach for population level identification of condition-associated T-cell receptor β-chain CDR3 sequences

The paper introduces a clustering-based method to identify condition-associated TCR CDR3 sequences by comparing immune repertoires across populations.

Genetics of vaccination-related narcolepsy

The paper identifies genetic risk variants associated with vaccination-related narcolepsy using genomic data from cases and controls.

HLA RNAseq reveals high allele-specific variability in mRNA expression

The paper uses RNA sequencing to analyze allele-specific expression levels of HLA genes in 50 healthy individuals, finding significant differences in mRNA expression between HLA alleles.