Author

Patrícia Kellen Martins Oliveira Brito

Universidade de São PauloORCID 0000-0002-1406-4385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Gabriela Yamazaki de CamposiD· 2 shared Gustavo Henrique GoldmaniD· 2 shared Júlia Garcia GuimarãesiD· 2 shared Michele Procópio MachadoiD· 2 shared Patrícia Vianna Bonini Palma· 2 shared Thaila Fernanda dos ReisiD· 2 shared Thiago Aparecido da SilvaiD· 2 shared Angelina S. PalmaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Gabriela Yamazaki de CamposORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Enhanced antifungal activity of NK-92 cells against Candida albicans mediated by a mannan-specific chimeric antigen receptor

Gabriela Yamazaki de Campos, Júlia Garcia Guimarães, Michele Procópio Machado, Patrícia Kellen Martins Oliveira Brito, Ben Shin, Antonio Di Maio, Douglas dos-Santos, Patrícia Vianna Bonini Palma, Thaila Fernanda dos Reis, Gustavo Henrique Goldman, Angelina S. Palma, Stephen Matthews, Ten Feizi, Yan Liu, Thiago Aparecido da Silva

This paper develops and tests CAR-NK-92 cells targeting Candida albicans mannan, showing enhanced antifungal activity and reduced fungal burden in mice.

Cytotherapy · May 17, 2025Peer-reviewedBioengineering

A novel Mannan-specific chimeric antigen receptor M-CAR redirects T cells to interact with Candida spp. hyphae and Rhizopus oryzae spores

Júlia Garcia Guimarães, Gabriela Yamazaki de Campos, Michele Procópio Machado, Patrícia Kellen Martins Oliveira Brito, Thaila Fernanda dos Reis, Gustavo Henrique Goldman, Patrícia Vianna Bonini Palma, Thais Fernanda de Campos Fraga‐Silva, Daniela Cardoso Umbelino, James Venturini, Thiago Aparecido da Silva

This paper develops a Mannan-specific chimeric antigen receptor (M-CAR) that activates T cells against Candida spp. and Rhizopus oryzae, enhancing immune response against fungal infections.

Bioengineered · Feb 1, 2025Peer-reviewedBioengineering