Antonio Di Maio

This study reports the structures of a mammalian gamma-CoV spike in closed and open conformations, revealing conserved mechanisms of spike dynamics and lipid binding's role in stabilizing the closed state.

This study examines mutations in H5N1 influenza virus HA that affect receptor binding and antiviral susceptibility, finding reduced sialic acid binding correlates with mucus evasion and antiviral resistance.

The paper reveals how long-chain heparan sulfate (HS) facilitates paracrine GDNF-GFRα1 signaling by forming a multi-protein complex with RET, essential for signaling in trans but not in cis.

This study shows that secreted M protein, not cell-surface M protein, is critical for lymphatic survival and systemic infection of Streptococcus pyogenes in mice.

This paper develops and tests CAR-NK-92 cells targeting Candida albicans mannan, showing enhanced antifungal activity and reduced fungal burden in mice.

This study characterizes Cucumis melo agglutinin (CMA1), revealing its glycan-binding specificity and 3D structure, and compares it to the R-type lectin RCA1.