Thomas Santarius

This study identifies a mechanism by which skull bone marrow-derived HSPCs and CD4+ T cells promote immunotolerance in childhood brain tumours, showing that antibody therapy targeting CSF cytokines can disrupt this process and induce tumour regression.

This study investigates the spatial-temporal evolution of extrachromosomal DNA (ecDNA) in glioblastoma, showing that EGFR ecDNA drives tumor evolution and identifies a potential therapeutic window for early intervention.

This study identifies anatomical variations in trigeminal and facial nerve branches and foramina using dissection and microCT, providing safe distances for surgical procedures.

The paper profiles gene expression in human microglia from 141 patients, identifies population shifts in acute brain injury, maps eQTLs, and fine-maps Alzheimer's risk variants using hIPSC-derived macrophages.

This study identifies two molecular subgroups of anaplastic meningioma with distinct survival outcomes and links them to specific genetic mutations.