Author

Elizabeth Alexandra Cooper

University of CambridgeORCID 0000-0002-6519-4753Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Richard J. GilbertsoniD· 3 shared Jason EigenbroodiD· 2 shared Jennifer C. ColemaniD· 2 shared Jessica TayloriD· 2 shared Katherine Elizabeth MasihiD· 2 shared Linda Hu· 2 shared Michael D. TayloriD· 2 shared Sigourney Bonner· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersDevelopmental Biology

Richard J. GilbertsonORCID

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Author profile →

3 papers

Recent·Most cited

Ependymomas are cancers of the pre-neural crest/roof plate lineage

Polina Balin, Sachin A Kumar, Riley Galton, Alberto Delaidelli, Wilda Orisme, Parthiv Haldipur, Ncedile Mankahla, Amr M. Saadeldin, Nik von Krosigk, Maria Claudia Vladoiu, Anders Wilder Erickson, Meyer Barembaum, Jake Millman, Amy J Banks, Jeffrey T Joseph, , Michael D. Taylor

The paper identifies ependymomas as originating from the pre-neural crest/roof plate lineage using single-cell transcriptomics and lineage tracing.

bioRxiv · Jul 14, 2026 · PreprintDevelopmental Biology

Childhood brain tumours instruct cranial haematopoiesis and immunotolerance

Elizabeth Alexandra Cooper, David A Posner, Colin Y.C. Lee, Linda Hu, Sigourney Bonner, Jessica Taylor, Oscar Baldwin, Rocío Jiménez‐Guerrero, Katherine Elizabeth Masih, Katherine Wickham-Rahrmann, Jason Eigenbrood, Gina Ngo, Luca Porcu, Valar Nila Roamio Franklin, Clive S. D’Santos, , Richard J. Gilbertson

This study identifies a mechanism by which skull bone marrow-derived HSPCs and CD4+ T cells promote immunotolerance in childhood brain tumours, showing that antibody therapy targeting CSF cytokines can disrupt this process and induce tumour regression.

bioRxiv · Sep 25, 2025 · PreprintImmunology

Natural language processing charts transcriptome evolution to design combination cancer therapies

Amir Jassim, Birgit V. Nimmervoll, Sabrina Terranova, Erica Nathan, Linda Hu, Jessica Taylor, Katherine Elizabeth Masih, Lisa Ruff, Matilde Duarte, Elizabeth Cooper, Gunjan Katyal, Melika Akhbari, Reuben J. Gilbertson, Jennifer C. Coleman, Joseph S. Toker, , Richard J. Gilbertson

This paper introduces RECODR, a computational pipeline that tracks transcriptome changes in cancer development and treatment to predict resistance mechanisms and design effective therapies.

Cancer Cell · Jun 26, 2025Peer-reviewedCancer Biology