Salvatore Di Giorgio

This study investigates the interaction between m6A and A-to-I RNA modifications in macrophages, showing that ~60% of genes are m6A-modified and ~12% have A-to-I editing sites, with ~10% overlapping.

The paper introduces SNAP-CDAR-S, a cytidine-to-uridine RNA base editor that outperforms RESCUE-S in editing efficiency and pathway perturbation.

The paper identifies RNA editing signatures in SARS-CoV-2 transcriptomes, suggesting host deaminases like ADAR and APOBEC contribute to antiviral defense and viral evolution.

This study identifies driver mutations in cancer by analyzing mutational likeliness and entropy, distinguishing them from passenger mutations and differentiating gain and loss of function mutations.