Filippo Martignano

This study identifies three leukaemia stem cell subtypes in paediatric AML and shows that combining CLEC12A and CD84 targets all subtypes while sparing healthy cells.

This study demonstrates the ability to detect cell-of-origin and cancer-specific methylation features from cell-free DNA using Oxford Nanopore sequencing.

The paper identifies RNA editing signatures in SARS-CoV-2 transcriptomes, suggesting host deaminases like ADAR and APOBEC contribute to antiviral defense and viral evolution.