Author
University of CambridgeORCID 0000-0002-1421-5569Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Karolina Matulewska-Sobczuk, Katja Bernfur, Dev Thacker…·Lei Ortigosa-Pascual
This study shows that sequence imperfections in synthetic Aβ42 peptides cause differences in aggregation behavior compared to recombinant Aβ42.
Matthew W. Cotton, Shriram Venkatesan, Joseph S. Beckwith…·Georg Meisl
The paper identifies a cellular tipping point between aggregate accumulation and removal as a universal feature of neurodegeneration, validated through live-cell assays and super-resolution imaging.
Danny D. Sahtoe, Ewa A. Andrzejewska, Hannah L. Han…·David A. Baker
The paper designs peptide traps that bind amyloidogenic segments in {beta}-strand and {beta}-hairpin conformations, effectively blocking fibril assembly for A{beta}42.