Takehiko Ogawa

The paper uses live imaging and mathematical modeling to show how self-organization of cell turnover in mouse testes sustains sperm production through phase waves and retinoic acid signaling.

This study evaluates an in vitro testis organ culture system for assessing cisplatin-induced testicular toxicity and recovery, showing it can replace animal experiments.

The paper uses single-cell RNA-sequencing to analyze in vitro cultured testes and identifies an inflammatory response in immune and somatic cells during early spermatogenesis.