Yuting I. Li

This study shows that early zebrafish embryo geometry guides asymmetric cell divisions and patterns zygotic genome activation, influencing cell cycle timing and developmental robustness.

The paper shows that meroblastic cleavage in zebrafish embryos involves a two-step process with mechanical uncoupling and cadherin-mediated adhesion, distinct from canonical cytokinesis.

The paper shows that coupling cell proliferation to the segmentation clock ensures uniform PSM growth and precise somite scaling in mouse embryos.

The paper uses live imaging and mathematical modeling to show how self-organization of cell turnover in mouse testes sustains sperm production through phase waves and retinoic acid signaling.