Shosei Yoshida

The paper traces individual PGC clones in mice to show early stochastic bottlenecks shape clonal contributions and reproductive success.

The paper uses live imaging and mathematical modeling to show how self-organization of cell turnover in mouse testes sustains sperm production through phase waves and retinoic acid signaling.

The paper uses spatial transcriptomics to map the temporal dynamics of the seminiferous epithelial cycle in mouse testis, revealing synchronized transcriptional patterns between Sertoli and germ cells.

This study identifies a foetal-like state 0B in human spermatogonial stem cells that maintains a suppressive transcriptomic program, contrasting with rodent models where this state is not maintained into adulthood.

This study identifies PRC1's role in maintaining adult undifferentiated spermatogonia by directing PRC2-H3K27me3 deposition to prevent differentiation and sustain slow cycling.

The paper identifies branched germline cyst structures in mice and shows they facilitate oocyte determination through directional cytoplasmic transport and cyst fragmentation.

This study identifies EXOC1's role in regulating pseudopod formation in spermatogonia and syncytium formation in spermatocytes in mice, highlighting its interaction with Rac1 and SNAP23/STX2.