Zoe Hall

This study investigates the role of hepatic HIF2α in MASLD, finding that its deletion leads to extra-hepatic complications like cardiac dysfunction and lean mass loss without protecting against liver disease progression.

The paper uses multimodal imaging to show that lysosomes act as a reservoir for PARP inhibitors, leading to heterogeneous drug distribution and response in ovarian cancer.

This paper shows MmpL3 from M. smegmatis forms dimers in various membrane mimetic systems, contradicting previous structural studies suggesting monomerism.