Elina Nürnberg

A synthetic xeno-free extracellular matrix surrogate supports robust human induced pluripotent stem cell maintenance and multilineage differentiation

This study demonstrates that BIOINSTRUCT, a synthetic extracellular matrix surrogate, supports robust human iPSC maintenance and multilineage differentiation comparable to Matrigel.

Advanced 3D spheroid-based skin models and deep-learning based image analysis enable in-depth investigation of keratinocyte differentiation and barrier function

The paper introduces 3D spheroid-based skin models and a deep-learning pipeline to study keratinocyte differentiation and barrier function, identifying NHK-E6/E7 as the best alternative to primary keratinocytes.

From in vitro to in silico: a pipeline for generating virtual tissue simulations from real image data

The paper develops an accessible pipeline for generating virtual tissue simulations from real 3D image data using open-source software and the Cellular Potts Model.

A Multiparametric Analysis Reveals Differential Behavior of Spheroid Cultures on Distinct Ultra-Low Attachment Plates Types

This study compares spheroid formation and behavior across six ultra-low attachment plate types using four human cell lines, finding size and eccentricity differences that suggest plate type impacts experimental outcomes.