Author

David C. Hooper

Massachusetts General HospitalORCID 0000-0002-1444-9939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Erica Seiguer ShenoyiD· 2 shared Virginia PierceiD· 2 shared Abigail L. MansoniD· 1 shared Adrianne D. GladdeniD· 1 shared Alejandro PirontiiD· 1 shared Andrew Bruce OnderdonkiD· 1 shared Ashlee M. EarliD· 1 shared Bennett M. ShawiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Erica Seiguer ShenoyORCID

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2 papers

Recent·Most cited

Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance

Rauf Salamzade, Abigail L. Manson, Bruce J. Walker, Thea Brennan-Krohn, Colin J. Worby, Peijun Ma, Lorrie L. He, Terrance Shea, James Qu, Sinéad B. Chapman, Whitney Howe, Sarah Young, Jenna I. Wurster, Mary Louise Delaney, Sanjat Kanjilal, , Ashlee M. Earl

The paper develops a method to trace horizontal gene transfer and persistence of carbapenem resistance genes across bacterial species using genomic data from clinical isolates.

Genome Medicine · Apr 4, 2022Peer-reviewedGenomics

DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencing

Kim A. Lagerborg, Erica Normandin, Matthew R. Bauer, Gordon C. Adams, Katherine Figueroa, Christine Loreth, Adrianne D. Gladden, Bennett M. Shaw, Leah R. Pearlman, Erica Seiguer Shenoy, David C. Hooper, Virginia Pierce, Kimon C. Zachary, Daniel J. Park, Bronwyn L. MacInnis, , Katherine J. Siddle

The paper introduces DNA spike-ins to detect contamination in SARS-CoV-2 amplicon-based sequencing and demonstrates their utility in a real-world outbreak investigation.

bioRxiv · Mar 16, 2021 · PreprintMolecular Biology