Bronwyn L. MacInnis

The paper evaluates the impact of drug resistance mutations on antimalarial drug resistance and fitness in Plasmodium falciparum isolates from Senegal using genetic and phenotypic assays.

Delphy provides a fast, scalable Bayesian phylogenetic analysis tool for outbreak tracking, achieving 1,000x speedups while maintaining state-of-the-art accuracy.

This study uses genomic data from 8746 SARS-CoV-2 genomes across 33 African countries to show that most epidemics were initiated by European importations and later driven by local transmission and mobility, leading to the spread of variants of concern.

The paper introduces DNA spike-ins to detect contamination in SARS-CoV-2 amplicon-based sequencing and demonstrates their utility in a real-world outbreak investigation.

The paper identifies a blood protein biomarker signature to distinguish bacterial from viral/malaria pneumonia in children in a malaria-endemic setting, with high sensitivity and specificity.

The paper uses metagenomic sequencing to identify a yellow fever outbreak in Edo State, Nigeria, from undiagnosed fever cases.

The paper analyzes mumps virus circulation in the US using genomic data to show multiple co-circulating lineages and transmission patterns, but finds no evidence of vaccine escape variants.

This study detects de novo mutations in Plasmodium falciparum to reconstruct disease transmission pathways and identify clade expansions not detectable with previous methods.

The paper sequences genomes of 765 malaria vector mosquitoes to study genetic diversity and insecticide resistance.

This study sequenced 110 Zika virus genomes from 10 countries, revealing rapid expansion in Brazil, multiple introductions into other regions, and undetected circulation before confirmed cases.