Author

Aurélia Huyghe

Centre de Recherche en Cancérologie de LyonORCID 0000-0002-1450-925XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Fabrice LavialiD· 3 shared Emile ZakieviD· 2 shared Léo Claret· 2 shared Nicolas GadotiD· 2 shared Yann TapponnieriD· 2 shared Aneta Trajkova· 1 shared Annie AdraitiD· 1 shared Antoine SeyveiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

Fabrice LavialORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintDec 23, 2025

A ligand/receptor trafficking clock governs self-renewal and abscission dynamics in pluripotent stem cells

Debora Libetti, Noémie Combémorel, Emma Fraimbault…·Fabrice Lavial

The paper identifies a ligand/receptor trafficking clock in pluripotent stem cells that regulates self-renewal and abscission dynamics through cyclic turnover of Netrin-1 and its receptors.

DOI 10.64898/2025.12.22.695902

mousehuman

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Cell BiologybioRxivPreprintDec 22, 2025

The Pioneer Transcription Factor Oct4 Differentially Co-opts Bcl11a and Bcl11b to Regulate Reprogramming to Pluripotency

Aneta Trajkova, Emile Zakiev, Maria Grazia Mendoza-Ferri…·Fabrice Lavial

This study identifies how Oct4 differentially co-opts Bcl11a and Bcl11b to regulate reprogramming to pluripotency by revealing their opposing roles in cell fate conversion.

DOI 10.64898/2025.12.19.694617

mousebulk RNA-seq

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Developmental BiologyNature CommunicationsPeer-reviewedJan 23, 2023

RSL24D1 sustains steady-state ribosome biogenesis and pluripotency translational programs in embryonic stem cells.

Sébastien Durand, Marion Bruelle, Fleur Bourdelais…·Mathieu Gabut

This study identifies RSL24D1 as a key regulator of ribosome biogenesis and pluripotency in mouse embryonic stem cells, showing its role in maintaining self-renewal and suppressing differentiation.

21 citations

mousebulk RNA-seq

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