Fabrice Lavial

Netrin-1 Acts as a Guardian of Naive Pluripotency in Human Embryonic Stem Cells

This study shows Netrin-1 supports naive pluripotency in hESCs by modulating epigenetic and signaling pathways, with effects dependent on culture conditions.

A ligand/receptor trafficking clock governs self-renewal and abscission dynamics in pluripotent stem cells

The paper identifies a ligand/receptor trafficking clock in pluripotent stem cells that regulates self-renewal and abscission dynamics through cyclic turnover of Netrin-1 and its receptors.

The Pioneer Transcription Factor Oct4 Differentially Co-opts Bcl11a and Bcl11b to Regulate Reprogramming to Pluripotency

This study identifies how Oct4 differentially co-opts Bcl11a and Bcl11b to regulate reprogramming to pluripotency by revealing their opposing roles in cell fate conversion.

RSL24D1 sustains steady-state ribosome biogenesis and pluripotency translational programs in embryonic stem cells.

This study identifies RSL24D1 as a key regulator of ribosome biogenesis and pluripotency in mouse embryonic stem cells, showing its role in maintaining self-renewal and suppressing differentiation.