Nicolas Gadot

The paper examines the spatial organization of dendritic cell subsets in NSCLC patients treated with anti-PD1 and finds that cDC1-driven patterns correlate with prolonged ICB response.

The paper identifies a ligand/receptor trafficking clock in pluripotent stem cells that regulates self-renewal and abscission dynamics through cyclic turnover of Netrin-1 and its receptors.

This study identifies how Oct4 differentially co-opts Bcl11a and Bcl11b to regulate reprogramming to pluripotency by revealing their opposing roles in cell fate conversion.

This study identifies Netrin-1 as a factor promoting sympathetic axon growth in pancreatic precancerous lesions, with its inhibition accelerating lesion progression.

This study identifies HERV-derived epitopes as potential targets for T-cell immunotherapies in ovarian cancer, showing their expression in tumors and immunogenicity in patients.