Molecular BiologybioRxivPreprint
A CRISPR-based genome-wide screen for adipogenesis reveals new insights into mitotic expansion and lipogenesis.
Rachel E. Turn, Keren I. Hilgendorf, Carl T. Johnson…·Peter K. Jackson
The paper uses a CRISPR-based screen in 3T3-L1 cells to identify regulators of adipogenesis, finding that protein translation and stability mechanisms are critical for adipocyte expansion and lipogenesis.
3 citations