Mohammad Ovais Aziz‐Zanjani

The paper uses Metabolic STAMP to map GPCR signaling pathways in β-cells, revealing distinct kinase programs and phospho-signatures that modulate insulin secretion.

This study identifies RSG1/CPLANE2 as a causative gene for human ciliopathy and shows its role in ciliary transition zone assembly.

The paper develops STAMP to study temporal-spatial signaling in quiescence by synchronizing ciliogenesis and G0 transition with microscopy and phospho-proteomics, revealing transient phosphorylations in cellular functions.

The paper uses a CRISPR-based screen in 3T3-L1 cells to identify regulators of adipogenesis, finding that protein translation and stability mechanisms are critical for adipocyte expansion and lipogenesis.