Proteome-Driven Phenotyping of Identified Single Neurons in Intact Brain Tissue by Aspiration Patch Proteomics
Nicolas C. Johnson, Sam B. Choi, Juan Zegers-Delgado…·Péter Nemes
This paper introduces aspiration patch proteomics to profile single neurons in intact brain tissue, identifying over 1,000 proteins and enabling subtype-level proteome phenotyping without cell dissociation.