Author

Jinguo Li

ORCID 0000-0002-1465-6786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Dengfeng DouiD· 2 shared Andrew Wood· 1 shared Anping Guo· 1 shared Chuan LiuiD· 1 shared Guansai LiuiD· 1 shared Guizhi Liu· 1 shared James B. MurrayiD· 1 shared Jian Liu· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Dengfeng DouORCID

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2 papers

Recent·Most cited

Cell BiologyACS Chemical BiologyPeer-reviewedApr 18, 2025

Chemically Induced Nuclear Pore Complex Protein Degradation via E3 Ligase TRIM21

Xiaomei Li, Qingyang Wang, Anping Guo…·Dengfeng Dou

This study identifies small-molecule ligands for TRIM21, an E3 ligase, demonstrating their ability to degrade nuclear pore complex proteins and induce cell death in cancer cells.

27 citationstop 2%

humanproteomics

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BiochemistryACS Chemical BiologyPeer-reviewedApr 9, 2025

TRIM21-NUP98 interface accommodates structurally diverse molecular glue degraders

Yalong Cheng, Longzhi Cao, Panrui Lu…·Ting Han

The paper identifies multiple molecular glue degraders that target the TRIM21-NUP98 interface, showing its ability to accommodate structurally diverse compounds.

15 citationstop 4%

experimental assaydrug response / drug discovery

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