ImmunologybioRxivPreprint
Zα domain-dependent ZBP1 condensate formation induces an amyloidal necroptotic signalling complex
Josephine Nemegeer, Aynur Soenmez, Evelien Dierick…·Jonathan Maelfait
This study shows that ZBP1 condensate formation, driven by Z domain binding to Z-RNA, promotes necroptotic cell death to restrict HSV-1 infection.
3 citations