Author

Lei Yang

Indiana University IndianapolisORCID 0000-0002-1479-2374Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lei Yang5 papers · Chinese Center For Disease Control and Prevention

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Jun WaniD· 3 shared Sheng LiuiD· 3 shared Elnaz PashaeiiD· 2 shared Xin LüiD· 2 shared Yong ZangiD· 2 shared Cheng WangiD· 1 shared Chenglong LiiD· 1 shared Edward R. SimpsoniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioinformatics

Jun WanORCID

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3 papers

Recent·Most cited

BioinformaticsNucleic Acids ResearchPeer-reviewedJun 13, 2025

DiCE: Differential Centrality-Ensemble Analysis Based on Gene Expression Profiles and Protein-Protein Interaction Network

Elnaz Pashaei, Sheng Liu, Kailing Li…·Jun Wan

DiCE identifies disease-associated genes by combining differential expression with network centrality analysis, validated on prostate cancer datasets to find genes correlated with disease-free survival.

14 citationstop 4%

humanprotein structure

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BioinformaticsBriefings in BioinformaticsPeer-reviewedSep 10, 2024

CDHu40: a novel marker gene set of neuroendocrine prostate cancer (NEPC)

Sheng Liu, Hye Seung Nam, Ziyu Zeng…·Jun Wan

The paper identifies a novel marker gene set, CDHu40, for neuroendocrine prostate cancer (NEPC) using gene expression and PPI network analysis, showing strong prognostic significance.

3 citations

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJan 20, 2022

SARS-CoV-2 Viral Genes Compromise Survival and Functions of Human Pluripotent Stem Cell-derived Cardiomyocytes via Reducing Cellular ATP Level

Juli Liu, Yucheng Zhang, Shiyong Wu…·Lei Yang

This study shows SARS-CoV-2 genes Nsp6, Nsp8, and M reduce ATP levels in hPSC-CMs, causing apoptosis and dysfunction, and identifies drugs that may counteract these effects.

DOI 10.1101/2022.01.20.477147

humanbulk RNA-seq

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