Author

Ruijie Liu

Utrecht UniversityPrimary ORCID profile (0000-0002-1489-1022 · 4 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Ruijie LiuiD4 papers · St Vincents Institute of Medical Research

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adela KarhanovaiD· 1 shared Alex Moore· 1 shared Aliaksei Z Holik· 1 shared Andressa Pelster Jose· 1 shared Anna S. AkhmanovaiD· 1 shared Charity W Law· 1 shared Daan Morren· 1 shared Gordon K Smyth· 1 shared

Activity by Year

2016-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Adela KarhanovaORCID

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2 papers

Recent·Most cited

Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling

Joyce C. M. Meiring, Varsha Mahapatra, Molly S. C. Gravett, Daan Morren, Harriet A. J. Saunders, Sung Ryul Choi, Andressa Pelster Jose, Adela Karhanova, Ioanna Metallidou, Alex Moore, Marel F.M. Spoelstra, Ruijie Liu, Matteo Giono, Saishree S. Iyer, J. Fernando Díaz, , Anna S. Akhmanova

This study shows taxanes induce conformational changes in microtubules, releasing GEF-H1 and activating RhoA signaling, leading to actin remodeling.

bioRxiv · Dec 23, 2025 · PreprintCell Biology

RNA-seq mixology: designing realistic control experiments to compare protocols and analysis methods

Aliaksei Z Holik, Charity W Law, Ruijie Liu, Zeya Wang, Wenyi Wang, Jaeil Ahn, Marie-Liesse Asselin-Labat, Gordon K Smyth, Matthew E Ritchie

This paper introduces an RNA-seq mixture experiment using two cancer cell lines to benchmark library preparation kits and analysis methods, finding that total RNA kits and voom with quality weights perform best.

bioRxiv · Jul 19, 2016Genomics