GenomicsbioRxivPreprint
Chromatin-associated RNA Dictates the ecDNA Interactome in the Nucleus
Zhengyu Liang, Collin Gilbreath, Wenyue Liu…·Xiang‐Dong Fu
The paper shows that ecDNA interactomes are shaped by nascent RNA, with PVT1 and MYC ecDNA using noncoding RNA for trans-activation, while EGFR ecDNA is less effective due to efficient splicing.
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