Author

Zhengyu Liang

Southern University of Science and TechnologyORCID 0000-0002-3307-0959Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Christopher M. AdamsiD· 1 shared Collin GilbreathiD· 1 shared Danni CheniD· 1 shared Dong‐Er ZhangiD· 1 shared Fhujjen Barroga· 1 shared Ju CheniD· 1 shared Mao YeiD· 1 shared Michael Q. ZhangiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Christopher M. AdamsORCID

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2 papers

Recent·Most cited

Transcriptional Readthrough at Atf4 Locus Suppresses Rps19bp1 and Impairs Heart Development

Zengming Zhang, Tongbin Wu, Zeyu Chen, Danni Chen, Zhengyu Liang, Christopher M. Adams, Yusu Gu, Mao Ye, Fhujjen Barroga, Sylvia Μ. Evans, Xiaohai Zhou, Ju Chen

The paper shows that cardiac defects in ATF4 knockout mice result from unintended Rps19bp1 downregulation due to transcriptional readthrough, not loss of ATF4 function.

Cardiovascular Research · Nov 14, 2025Peer-reviewedGenetics

Chromatin-associated RNA Dictates the ecDNA Interactome in the Nucleus

Zhengyu Liang, Collin Gilbreath, Wenyue Liu, Yan Wang, Michael Q. Zhang, Dong‐Er Zhang, Sihan Wu, Xiang‐Dong Fu

The paper shows that ecDNA interactomes are shaped by nascent RNA, with PVT1 and MYC ecDNA using noncoding RNA for trans-activation, while EGFR ecDNA is less effective due to efficient splicing.

bioRxiv · Jul 27, 2023 · PreprintGenomics