Author

Joel Tong

The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & TechnologyORCID 0000-0002-1506-5777Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Thomas J. KodadekiD· 2 shared Bin-Bin SchelliD· 1 shared Isuru M. JayalathiD· 1 shared J. Monty WatkinsiD· 1 shared James M. BurkeiD· 1 shared Madeline BalzariniiD· 1 shared Weijun GuiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Thomas J. KodadekORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryCell chemical biologyPeer-reviewedApr 1, 2026

Assessing the Suitability of Deubiquitylases As Substrates For Targeted Protein Degradation

Joel Tong, J. Monty Watkins, James M. Burke, Thomas J. Kodadek

This study evaluates whether deubiquitylases (DUBs) can be effectively degraded by PROTACs, finding that some DUBs are degradable while others resist degradation due to auto-deubiquitylation or poor proteasome substrate properties.

5 citationstop 1%

humanexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJul 19, 2023

Chemically Induced Degradation of Native Proteins by Direct Recruitment to the 26S Proteasome

Madeline Balzarini, Weijun Gui, Isuru M. Jayalath…·Thomas J. Kodadek

This study demonstrates a method to degrade native proteins by directly recruiting them to the proteasome without requiring ubiquitylation.

12 citations

proteomicsexperimental assay

𝕏 PostBluesky