Cell BiologybioRxivPreprint
Thioredoxin-1 inhibits granulosa cell ferroptosis to rescue ovarian aging through mitophagy-dependent activation of BNIP3L
Wenting Yang, Xiaorui Zhang, Rui Xu…·Guoqing Tong
This study shows that Thioredoxin-1 prevents granulosa cell ferroptosis by promoting mitophagy, thereby improving ovarian aging and fertility in mice.