Author

Simona Plesselova

Sanford ResearchORCID 0000-0002-1517-5271Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Darci M. FinkiD· 2 shared Hailey Axemaker· 2 shared Kristin Calar· 2 shared Pilar de la PuenteiD· 2 shared Amrita Bhagia· 1 shared Congzhou WangiD· 1 shared Emma Sahly· 1 shared Etienne Z. GnimpiébaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

Darci M. FinkORCID

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2 papers

Recent·Most cited

Recapitulating physiologically relevant oxygen levels and extracellular matrix remodeling in patient-derived tumor-immune tunable models reveal targeting opportunities for immunologically cold high-grade serous tumors

Simona Plesselova, Hailey Axemaker, Kristin Calar, Oduduabasi Isaiah, Jared W. Wollman, Somshuvra Bhattacharya, Etienne Z. Gnimpiéba, Darci M. Fink, Congzhou Wang, Maria Bell, Pilar de la Puente

This study develops patient-derived tumor-immune models that mimic hypoxia and extracellular matrix changes, revealing TGF-β targeting opportunities to improve immune infiltration in cold tumors.

bioRxiv · Jun 23, 2025 · PreprintBioengineering

Multicompartmentalized microvascularized tumor-on-a-chip to study tumor-stroma interactions and drug resistance in ovarian cancer

Simona Plesselova, Kristin Calar, Hailey Axemaker, Emma Sahly, Amrita Bhagia, Jessica L. Faragher, Darci M. Fink, Pilar de la Puente

This paper develops a tumor-on-a-chip model to study ovarian cancer drug resistance by mimicking tumor-stroma interactions and compartmentalized microenvironment.

Cellular and Molecular Bioengineering · Sep 14, 2024Peer-reviewedBioengineering