Synapse-like Specializations at Dopamine Release Sites Orchestrate Efficient and Precise Neuromodulatory Signaling
Chandima Bulumulla, Deng Zhang, Deepika Walpita, Nirmala Iyer, Mark Eddison, David Ackerman, Hideo Otsuna, Xianling Zhao, Shuqin Zhang, Shihong Max Gao, Nan Wang, Abraham G. Beyene
This paper reveals that dopamine release is highly localized to synapse-like structures, challenging the idea that neuromodulators act diffusely.
Science Advances · Oct 2, 2026Peer-reviewedNeuroscience