David Ackerman

This paper reveals that dopamine release is highly localized to synapse-like structures, challenging the idea that neuromodulators act diffusely.

This study uses single-particle tracking and 3D FIB-SEM to reveal dynamics and organization of individual vimentin filaments within dense networks, showing bidirectional motion and minimal local co-alignment with microtubules.

The paper releases high-resolution 3D imaging and nucleus segmentations of seven tissues from a P7 mouse using FIB-SEM and machine learning.

This paper introduces a 2D nanofilm to visualize dopamine release with synaptic resolution and quantal sensitivity, revealing spatial patterns and colocalization with Bassoon in dendrites.

The paper presents a detailed connectome of the adult Drosophila central brain, including new methods for data analysis and biological insights into neural circuit organization.

A dense electron-microscopy reconstruction of half the fly central brain, with nearly every cell typed and queryable online, turns months of tracing partners into a database lookup.

The paper reconstructs 1,000 projection neurons in the mouse brain, revealing new cell types and organizational principles of long-range connectivity.