Author

Jordy Akkermans

University of AntwerpORCID 0000-0002-1533-9504Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 3 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniele BertoglioiD· 3 shared Alan MirandaiD· 2 shared Franziska ZajicekiD· 2 shared Alison R. WeissiD· 1 shared Annemie Van EetveldtiD· 1 shared Celia DomingueziD· 1 shared Jeroen A.J. VerhaegheiD· 1 shared Jodi L. McBrideiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Daniele BertoglioORCID

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Author profile →

3 papers

Recent·Most cited

Preclinical evaluation of CHDI-009R for quantification of mutant huntingtin aggregates

Franziska Zajicek, Liesbeth Everix, Annemie Van Eetveldt, Jeroen A.J. Verhaeghe, Stef De Lombaerde, Alan Miranda, Jordy Akkermans, Celia Dominguez, Vinod K. Khetarpal, Jonathan Bard, Longbin Liu, Steven G. Staelens, Daniele Bertoglio

This study evaluates [11C]CHDI-009R as a PET radioligand for quantifying mutant huntingtin aggregates in a mouse model of HD, showing high stability, reliability, and genotype differentiation.

Journal of Molecular Medicine · Dec 18, 2025Peer-reviewedNeuroscience

Prodromal pathogenesis of CLN7 Batten Disease revealed by multimodal biomarkers in macaques

William A. Liguore, Winde Hilven, Lili Lurye, Jordy Akkermans, Marion Decrop, Robert C. Zweig, Larry S. Sherman, Jodi L. McBride, Daniele Bertoglio, Alison R. Weiss

The paper characterizes early CLN7 disease in macaques using multimodal biomarkers, revealing region-specific brain changes and neurodegeneration markers.

bioRxiv · Dec 5, 2025 · PreprintNeuroscience

Identification of pre-synaptic density networks using SV2A PET imaging and ICA in healthy and diseased mice

Jordy Akkermans, Franziska Zajicek, Alan Miranda, Mohit H. Adhikari, Daniele Bertoglio

This paper applies ICA to SV2A PET data in mice to identify pre-synaptic density networks, showing age-related changes and disease impacts in HD models.

bioRxiv · Oct 19, 2022 · PreprintNeuroscience