Franziska Zajicek

This study evaluates [11C]CHDI-009R as a PET radioligand for quantifying mutant huntingtin aggregates in a mouse model of HD, showing high stability, reliability, and genotype differentiation.

This paper evaluates [18F]CHDI-650, a novel PET radiotracer, for imaging mutant huntingtin aggregates in HD mouse models, showing genotype discrimination at 3 and 9 months.

This paper applies ICA to SV2A PET data in mice to identify pre-synaptic density networks, showing age-related changes and disease impacts in HD models.

This paper develops a PET radioligand to visualize mutant huntingtin levels in the brain and assess therapeutic interventions in Huntington's disease.