Nicolas Borghi

The paper identifies PAX3's role in coupling metabolism and cell mechanics during neuroepithelial morphogenesis, showing mannose metabolism is critical for adherens junction function.

The paper measures actin cortex thickness and elasticity in live cells, finding a universal scaling law (E ~ h-2) that depends on actin filament volume fraction.

The paper shows chromosome condensation increases nuclear envelope tension, which is necessary for cyclin B1 translocation and dynein loading, enabling timely mitotic entry.

This study identifies a mechanochemical pathway linking cell density to epithelial migration via ERK, cPLA2, and mechanically regulated signaling from adhesions to the nucleus.