Martín Beaumont

This study shows that IgA-mediated bacterial aggregation at weaning prevents mucus penetration by commensal bacteria, while its disruption allows deeper bacterial encroachment.

This study shows that isovalerate, a gut microbiota metabolite, enhances epithelial barrier function in porcine ileum organoid-derived cell monolayers by upregulating immunity and absorptive cell markers while reducing stem cell and mucus genes.

This study maps transcriptome changes in rabbit intestinal epithelial cells during the suckling-to-weaning transition, revealing cell-type-specific responses to solid food intake.

This study uses scRNA-seq to show that ALI culture enhances goblet cell differentiation and reduces glycolysis in rabbit caecum organoids, more closely mirroring in vivo gene expression patterns.